Sulbutiamine, more effective mental performance

Published: admin | Format: 2017-02-27


As a synthetic derivative of thiamine, Sulbutiamine can cause a more effective treatment versus other analogues of Vitamin B1, because it helps increase the lipophilicity of Thiamine allowing an increase in Thiamine and Thiamine Esters in the brain, which means sulbutiamine is capable of better transportation across the blood-brain barrier where it can interact with your central nervous system.

Sulbutiamine is categorized as a nootropic which is a class of supplements shown to help improve memory, learning capacity, decision-making, concentration, focus, and is most frequently used in a nootropic stack with other supplements to boost energy levels and general brainpower. It has a positive effect on mood and is reported to improve mental performance when engaging in intellectually demanding tasks.

Benefits of intake Sulbutiamine

Creates more effective mental performance

Boost Mood

Improved  Memory function

Protective functions to neurons in the brain

Roles to play in weight control


sulbutiamine was demonstrated  that it can improve memory function via the potentiation of cholinergic, dopaminergic and glutaminergic transmission between neurons. This can be used to improve mental performance and boost mood. It has long been used as an over-the-counter nootropic to improve neurotransmission helps to improve reflexes, attention and mental alertness.

Due to its influence on acetylcholine and glutamate activity by Influencing D1 dopamine receptor function,  sulbutiamine aids in added cognitive benefits and create feelings of euphoria and pleasure.

Sulbutiamine was able to improve working memory and spatial memory when deficits are induced by the NMDA antagonist dizocilpine. It act as a very powerful anti -depressant for short periods of time without the upleasant side effects associated with caffeine, such as the jitters.

Sulbutiamine is also used for the treatment of asthenia and fatigue that is of non muscular origin, i.e. perceived fatigue in the brain. It can prevent drug induced memory deficits and improve object recognition and creates more effective communication between neurons. This tends to improve one’s attention levels and how alert the user feels.

Sulbutiamine can also be used to combat cognitive decline of other natures - for instance it can be used to prevent the amnesiac effects of dizocilpine, as well as cognitive performance in Alzheimer's patients and schizophrenics.

Incidentally, sulbutiamine has also been used as an appetite suppressant and a fat burner among dieters and bodybuilders. There are certainly a number of highly beneficial effects of sulbutiamine both for the brain and the body.Many athletes were using it as a legal performance enhancer in sports and it is quite popular in these communities.

In summary,  with the benefits of sulbutiamine, users experience an increase in focus, while combating feelings of anxiety and stress. This will allow you to feel more at ease, which is better for your mental health, and give you faster brain response, improved verbal articulation, increased motivation and a greater awareness.

Tips and date

One double blind placebo study involving post-infectious chronic fatigue patients suggested both 400mg or 600mg daily sulbutiamine may reduce fatigue levels.

Prescribed 400mg of sulbutiamine daily with their breakfast and usual anti-infective medication for 15 days, 51% patients had their symptoms completely resolved and the number of patients reporting severe, moderate and mild symptoms also decreased significantly.


Safety and Dosage

People using sulbutiamine may experience side effects such as mild agitation or an allergic skin rash. This is generally a result of taking an abnormally high dose.

The recommended dosage of sulbutiamine is usually  400mg-600 mg per day, and the maximum daily dosage is 600mg per day.


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